GRADE

The GRADE approach (Grading of Recommendations, Assessment, Development, and Evaluation) is a method of grading the quality of evidence and the strength of recommendations in guidelines. This approach is being used by many international organizations to produce rigorous and transparent Clinical Practice Guidelines and other health care recommendations.

The SOGC has adopted the GRADE methodology to evaluate the recommendations in each of its Clinical Practice Guidelines.

Below is additional information and helpful resources:


GRADE guidelines - Articles:

  • GRADE guidelines: 1. Introduction—GRADE evidence profiles and summary of findings tables

http://www.jclinepi.com/article/S0895-4356(10)00330-6/abstract

 

  • GRADE guidelines: 2. Framing the question and deciding on important outcomes

http://www.jclinepi.com/article/S0895-4356(10)00331-8/fulltext

 

  • GRADE guidelines: 3. Rating the quality of evidence

http://www.jclinepi.com/article/S0895-4356(10)00332-X/fulltext

 

  • GRADE guidelines: 4. Rating the quality of evidence—study limitations (risk of bias)

http://www.jclinepi.com/article/S0895-4356(10)00413-0/abstract

 

  • GRADE guidelines: 5. Rating the quality of evidence—publication bias

http://www.jclinepi.com/article/S0895-4356(11)00181-8/abstract

 

  • GRADE guidelines 6. Rating the quality of evidence—imprecision

http://www.jclinepi.com/article/S0895-4356(11)00206-X/abstract

 

  • GRADE guidelines: 7. Rating the quality of evidence—inconsistency

http://www.jclinepi.com/article/S0895-4356(11)00182-X/abstract

 

  • GRADE guidelines: 8. Rating the quality of evidence—indirectness

http://www.jclinepi.com/article/S0895-4356(11)00183-1/fulltext

 

  • GRADE guidelines: 9. Rating up the quality of evidence

http://www.jclinepi.com/article/S0895-4356(11)00184-3/fulltext

 

  • GRADE guidelines: 10. Considering resource use and rating the quality of economic evidence

http://www.jclinepi.com/article/S0895-4356(12)00134-5/abstract

 

  • GRADE guidelines: 11. Making an overall rating of confidence in effect estimates for a single outcome and for all outcomes

http://www.jclinepi.com/article/S0895-4356(12)00025-X/fulltext

 

  • GRADE guidelines: 12. Preparing Summary of Findings tables—binary outcomes

http://www.jclinepi.com/article/S0895-4356(12)00032-7/fulltext

 

  • GRADE guidelines: 13. Preparing Summary of Findings tables and evidence profiles—continuous outcomes

http://www.jclinepi.com/article/S0895-4356(12)00240-5/fulltext

 

  • GRADE guidelines: 14. Going from evidence to recommendations: the significance and presentation of recommendations

http://www.jclinepi.com/article/S0895-4356(12)00138-2/abstract

 

  • GRADE guidelines: 15. Going from evidence to recommendation—determinants of a recommendation's direction and strength

http://www.jclinepi.com/article/S0895-4356(13)00054-1/fulltext

 


GRADE Online Learning Modules:

https://cebgrade.mcmaster.ca/