The GRADE approach (Grading of Recommendations, Assessment, Development, and Evaluation) is a method of grading the quality of evidence and the strength of recommendations in guidelines. This approach is being used by many international organizations to produce rigorous and transparent Clinical Practice Guidelines and other health care recommendations.

The SOGC has adopted the GRADE methodology to evaluate the recommendations in each of its Clinical Practice Guidelines.

Below is additional information and helpful resources:

GRADE guidelines - Articles:

  • GRADE guidelines: 1. Introduction—GRADE evidence profiles and summary of findings tables


  • GRADE guidelines: 2. Framing the question and deciding on important outcomes


  • GRADE guidelines: 3. Rating the quality of evidence


  • GRADE guidelines: 4. Rating the quality of evidence—study limitations (risk of bias)


  • GRADE guidelines: 5. Rating the quality of evidence—publication bias


  • GRADE guidelines 6. Rating the quality of evidence—imprecision


  • GRADE guidelines: 7. Rating the quality of evidence—inconsistency


  • GRADE guidelines: 8. Rating the quality of evidence—indirectness


  • GRADE guidelines: 9. Rating up the quality of evidence


  • GRADE guidelines: 10. Considering resource use and rating the quality of economic evidence


  • GRADE guidelines: 11. Making an overall rating of confidence in effect estimates for a single outcome and for all outcomes


  • GRADE guidelines: 12. Preparing Summary of Findings tables—binary outcomes


  • GRADE guidelines: 13. Preparing Summary of Findings tables and evidence profiles—continuous outcomes


  • GRADE guidelines: 14. Going from evidence to recommendations: the significance and presentation of recommendations


  • GRADE guidelines: 15. Going from evidence to recommendation—determinants of a recommendation's direction and strength


GRADE Online Learning Modules: