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Clarification around Prescribing the TSEC of Conjugated Estrogens and Bazedoxifine Duavive

The SOGC has become aware that there are questions around how to prescribe the TSEC (tissue selective estrogen complex) of conjugated estrogens and bazedoxifine Duavive. Bazedoxifine provides endometrial protection. The TSEC does not require a progestin for endometrial protection; neither a progestin nor progesterone should be prescribed to a woman receiving Duavive.