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SOGC Statement on the Safety and Effectiveness of Doxylamine Pyridoxine (Diclectin)

The SOGC is aware of the recent debate arising from a recent publication by Dr. Nav Persaud, regarding the effectiveness of Diclectin. Our Clinical Committee has been asked to review the recent study, but much of the concern raised relate to data that we do not have access to. We hope that Health Canada or the U.S. Food and Drug Administration (FDA) will respond. 

For now, we are reassured that after extensive reviews by both Health Canada and Dr. Persaud, no safety concerns have been raised. The SOGC has not changed its recommendations for management of nausea and vomiting in pregnancy.